• Provides 500 mg of bromelain from pineapple stems per capsule • Supports healthy digestion by enhancing the breakdown of dietary proteins • Provides the clinical dose used in controlled trials for supporting musculoskeletal health • Bromelain is well-absorbed and retains enzymatic activity, allowing for systematic anti-inflammatory effects
Bromelain, found in pineapple stems, is a combination of multiple proteolytic enzymes classified as cysteine or thiol proteinases. Bromelain’s long history as a digestive aid is partly attributed to its protein-digesting ability over a wide pH range. However, it has also been shown to stimulate pancreatic enzyme production and improve epithelial integrity in experimental models.1,2
In addition to its function as a digestive enzyme, bromelain has been shown to be absorbed in the digestive tract and retain its enzymatic activity in the blood.3 Among its many enzymatic effects, bromelain has been shown to be a potent anti-inflammatory agent, reducing levels of inflammatory signals, such as tumour necrosis factor (TNF) and nuclear factor-kappa B (NF-kappaB).4–6
Bromelain’s anti-inflammatory, fibrinolytic, and analgesic effects mediate many of its musculoskeletal benefits as well. In an open-label trial, bromelain supplementation was shown to reduce acute knee pain as well as stiffness and function, with a dose-dependent effect.7 In another clinical trial of mild/moderate knee osteoarthritis, bromelain had similar efficacy to standard therapy at four weeks. By 16 weeks, improvements in pain, stiffness, and function were observed with bromelain supplementation.8 More rapid recovery and reduction of pain and swelling following multiple types of minor trauma have been reported with bromelain as well.9–11
Quantity
90 Capsules
Dose
Recommended Adult Dose: 1 capsule per day with food or as directed by a health care practitioner. Consult a health care practitioner for prolonged use.
<a name="p1"> </a><h3>Indications</h3>
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• Provides 500 mg of bromelain from pineapple stems per capsule • Supports healthy digestion by enhancing the breakdown of dietary proteins • Provides the clinical dose used in controlled trials for supporting musculoskeletal health • Bromelain is well-absorbed and retains enzymatic activity, allowing for systematic anti-inflammatory effects
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Cake\View\View->_evaluate() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/View/View.php, line 1179
Cake\View\View->_render() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/View/View.php, line 810
Cake\View\View->render() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Controller/Controller.php, line 790
Cake\Controller\Controller->render() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Controller/Controller.php, line 569
Cake\Controller\Controller->invokeAction() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Controller/ControllerFactory.php, line 140
Cake\Controller\ControllerFactory->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Controller/ControllerFactory.php, line 115
Cake\Controller\ControllerFactory->invoke() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/BaseApplication.php, line 325
Cake\Http\BaseApplication->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 86
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Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Middleware/CsrfProtectionMiddleware.php, line 176
Cake\Http\Middleware\CsrfProtectionMiddleware->process() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 82
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 67
Cake\Http\Runner->run() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Routing/Middleware/RoutingMiddleware.php, line 198
Cake\Routing\Middleware\RoutingMiddleware->process() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 82
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Routing/Middleware/AssetMiddleware.php, line 68
Cake\Routing\Middleware\AssetMiddleware->process() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 82
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Middleware/EncryptedCookieMiddleware.php, line 93
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Cake\Http\Server->run() /home/ndassist/nhpassist.com/webroot/index.php, line 40
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Dose
Recommended Adult Dose: 1 capsule per day with food or as directed by a health care practitioner. Consult a health care practitioner for prolonged use.
