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• Offers a full array of protective compounds from cruciferous vegetables, including I3C, DIM, and sulforaphane
• Provides a unique blend of botanicals that improve estrogen metabolism, shifting away from carcinogenic metabolites
• Supports detoxification of a variety of environmental toxins as well as naturally produced hormones by enhancing phase 1 and phase 2 liver enzymes
• Contains botanicals with potent anti-inflammatory activity
• Suitable for vegetarians/vegans
Each Vegetarian Capsule Contains:
Calcium D-Glucarate (d-Glucaric Acid Calcium Salt) : 75 mg
Indole-3-Carbinol (3-Hydroxymethylindole) : 75 mg
Green Tea Extract (Camellia sinensis) (leaf) (80% Catechins, 45% EGCG*, < 1% Caffeine) : 50 mg
Tomato Extract (Lycopersicon esculentum) (fruit) (5% Lycopene) : 50 mg
Broccoli Powder (Brassica oleracea var. italica) (aerial) (0.36% Sulforaphane) : 27.5 mg
DIM (3,3’-Diindolylmethane) : 25 mg
Turmeric Extract (Curcuma longa) (rhizome) (95% Curcuminoids) : 25 mg
Milk Thistle Extract (Silybum marianum) (seed) (50–60% Silymarin) : 25 mg
Rosemary 6:1 Extract (Rosmarinus officinalis) (leaf) : 12.5 mg
* Epigallocatechin-3-gallate
Vegetarian capsule (carbohydrate gum [cellulose ], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica.
EstroVantage EM provides a comprehensive formula of plant-based compounds that improve the metabolism of estrogen and its metabolites. Cruciferous vegetables contain a variety of glucosinolates, which some studies have associated with a reduction in cancer incidence when consumed in greater amounts, most likely by causing a shift in metabolism to less carcinogenic estrogen metabolites.1,2EstroVantage EM contains indole-3-carbinol (I3C) and its metabolite 3,3’-diindolylmethane (DIM), as well as sulforaphane from broccoli powder, all of which have been linked to lower rates of neoplastic changes and a more favourable estrogen profile.3-6Not only do these glucosinolates improve estrogen metabolism, they also reduce inflammation by targeting key signalling molecules, such as Nrf2 and NF- κ B.7,8
EstroVantage EM also includes other potent plant compounds that reduce inflammation and block carcinogenic pathways. Silymarin, a milk thistle extract, down-regulates gene products involved in the proliferation of tumour cells, along with their invasion, angiogenesis, and metastasis. In addition, it enhances glucuronidation and maintains glutathione levels.9-11 This unique combination provides green tea polyphenols, lycopene (tomato extract), turmeric and rosemary extracts, as well as calcium D-glucarate, all of which have been shown to favourably shift estrogen metabolism and reduce carcinogenic risk.12-14 Most recently, a randomized, double-blind, placebo-controlled crossover study demonstrated that taking this formula led to markedly higher urinary levels of the protective 2-OHE < sub > 1 < /sub > estrogen metabolite and lower levels of the more dangerous 16 α -OHE < sub > 1 < /sub > estrogen metabolite in premenopausal women.Most recently, a randomized, double-blind, placebo-controlled crossover study demonstrated that taking this formula led to markedly higher urinary levels of the protective 2-OHE < sub > 1 < /sub > estrogen metabolite and lower levels of the more dangerous 16 α -OHE < sub > 1 < /sub > estrogen metabolite in premenopausal women.15
90 Vegetarian Capsules
3 capsules once per day with food or as directed by a health care practitioner. Consult a health care practitioner for use beyond 12 weeks.
Disclaimer: This content is subject to change. The information is intended to inform and educate; it does not replace the medical evaluation, advice, diagnosis or treatment by a healthcare professional. www.nhpassist.com © 2014 NDAssist Inc. and/or its affiliates. All rights reserved.
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EstroVantage EM ®Indications
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• Offers a full array of protective compounds from cruciferous vegetables, including I3C, DIM, and sulforaphane IngredientsEach Vegetarian Capsule Contains: Quantity
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Dose3 capsules once per day with food or as directed by a health care practitioner. Consult a health care practitioner for use beyond 12 weeks. |
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