Indications

Curcumin-Pro™ provides antioxidants for the maintenance of good health and is used in herbal medicine to help relieve joint inflammation.

Ingredients

Medicinal ingredients (1 capsule):
Turmeric (95% curcuminoids) … 400mg
Bromelain 1000 GDU (pineapple) … 60mg
Lecithin (20% Phosphatidylcholine) … 125mg

Non-medicinal ingredients: Vegetable-grade magnesium stearate, vegetable capsule.

Description

Curcumin is a phytochemical derived from the spice turmeric. For thousands of years, turmeric has been one of the most commonly prescribed Ayurvedic remedies to treat arthritis-related inflammation. Curcuminoids in turmeric slow the enzymes that cause inflammation and give the spice it’s bright yellow colour.

Curcuminoids are also responsible for turmeric’s powerful antioxidant capabilities. Antioxidants neutralize free radicals (damaged rogue cells that debilitate more cells as they circulate) that go on to prompt the start of aging and disease in the body.

Human clinical trials have shown that the body’s absorption rate of curcumin when taken orally is low. To compensate, phosphatidylcholine from naturally-sourced lecithin and bromelain have been added to the formula to enhance absorption and support curcumin’s anti-inflammatory properties.

Quantity

60 vegetable capsules

Dose

Adults - Take 1 capsule 3 times per day away from food or as directed by a healthcare practitioner. For prolonged use, consult a healthcare practitioner.

Potential side effects/Safety

Cautions and Warnings:
Contraindicated in pregnant and breastfeeding women.
Caution advised before surgery.

Caution advised with medical conditions including gallstones, biliary tract obstructions, gastrointestinal lesions or ulcers and excess stomach acid.

Drug interactions:
Caution advised when used concurrently with anticoagulants, antibiotics or antiplatelet medications.

Side effects:
User should discontinue use if hypersensitivity, nausea, vomiting or diarrhoea occurs.

References

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Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB. Bioavailability of curcumin: problems and promises. Mol Pharm. 2007;4(6):807-818.

Cheng AL, Hsu CH, Lin JK, et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res. 2001;21(4B):2895-2900.

Duvoix A, Blasius R, Delhalle S, et al. Chemopreventive and therapeutic effects of curcumin. Cancer Lett. 2005;223(2):181-190.

Hong J, Bose M, Ju J, et al. Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase. Carcinogenesis. 2004;25(9):1671-1679.

Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. Multiple biological activities of curcumin: a short review. Life Sci. 2006;78(18):2081-2087.

Marczylo TH, Verchoyle RD, Cooke DN, Morazzoni P, Steward WP, Gescher AJ. Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine.Cancer Chemother Pharmacol. 2007 Jul;60(2):171-7. Epub 2006 Oct 19.

Moos PJ, Edes K, Mullally JE, Fitzpatrick FA. Curcumin impairs tumor suppressor p53 function in colon cancer cells. Carcinogenesis. 2004;25(9):1611-1617.

Somasundaram S, Edmund NA, Moore DT, Small GW, Shi YY, Orlowski RZ. Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res. 2002;62(13):3868-3875.

Sreejayan, Rao MN. Nitric oxide scavenging by curcuminoids. J Pharm Pharmacol. 1997;49(1):105-107.